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Eltrombopag restores trilineage hematopoiesis in refractory severe aplastic anemia that can be sustained on discontinuation of drug.

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Secondary outcomes included extubation time, length of stay in intensive care unit (ICU) and hospital, Simplified Acute Physiology Score (the ICU scoring system measuring the severity of disease for patients admitted to ICU), and major adverse events occurring during hospitalization.

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Aspergillus niger3) Penicillium chrysogenum4) Fusarium avenacum5) Neurospora sitoplilaD) Isolation of fungal metabolites of pharmaceutical importanceAspergillus nidulans and other fungi are used for isolation of secondarymetabolites.

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Effect of cyclosporine on prostacyclin synthesis by vascular tissue in rabbits.

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CyPA regulates the infection and replication of several viruses affecting humans.

Several controlled clinical trials conducted since the 1970s have proven the benefit of 2- to 3-month courses of oral cyclophosphamide (or chlorambucil) in patients with frequently relapsing minimal-change nephropathy; of note, azathioprine has not proven efficacious.

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Low level lasers such as the Q1000 that produce soliton waves carry electrons back to the damaged atoms and cells, helping to restore normal DNA composition and normal, positive soliton wave communications between cells.

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In addition, because abnormal cytogenetic clones can occur in up to 12% of patients with aplastic anemia, the presence of some clones in otherwise typical cases of aplastic anemia does not necessarily signify a diagnosis of myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML).

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The most common reasons for ineligibility were refusal to participate by the patient or the patient's physician (38 percent), inactivity of disease for more than two years (26 percent), use of contraindicated medication (15 percent), and renal insufficiency (9 percent).

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Lysosomal stability during phagocytosis of Aspergillus flavus spores by alveolar macrophages of cortisone-treated mice.

Diseases such as encephalitis, multiple sclerosis (MS), stroke or tumors induce deterioration of the BBB with devastating influence on neuronal function.

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Recently, it has been described that aripiprazole and its active metabolite, dehydroaripiprazole, but no risperidone, paliperidone, olanzapine and ziprasidone are strong P-gp inhibitors, in vitro, while in vivo their administration is unlikely to induce DDIs at the blood-brain-barrier, but the possibility of DDIs in the intestine cannot be neglected.

Honokiol caused cleavage of Mcl-1 and downregulation of XIAP, whereas Bad was markedly upregulated; and Bid, p-Bad, Bak, Bax, Bcl-2, and Bcl-xL were unchanged ().

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Now integrative proponents are switching gears after the research they were asking for did not turn out as they hoped, increasingly arguing that the problem is not their improbable modalities but the research technology itself.

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The main toxicity of cytotoxic chemotherapy in such patients is neutropenia and secondary sepsis.

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Research diagnostic criteria for temporomandibular disorders: review, criteria, examinations, and specifications: critique.

There are more than 100 recognized strains of oral human papillomavirus (HPV), a member of the papovavirus family, implicated in a variety of oral lesions (Regezi and Sciubba 1993).

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If the patient is unresponsive to high-dose H-1 antihistamines, adding these is unlikely to create a responsive individual.

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Laboratory Tests in the Diagnosis and Follow-Up of Pediatric Rheumatic Diseases: An Update.

Glutathione deficiency is associated with impaired survival in HIV disease.

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Effect of long-term immunosuppression in kidney-graft recipients on cancer incidence: randomised comparison of two cyclosporin regimes.

In this hypothesis, the maturation arrest is the result of the additional depletion of thymocytes that normally survive by positive selection, whereas the impaired self-tolerance induction is caused by an increased survival of thymocytes that normally undergo negative selection.

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The lack of ergosterol alters membrane fluidity and steric relationships for selected membrane-associated enzymes and results in the alteration of the synthetic pathway and the accumulation of phospholipids and unsaturated fatty acids within the fungal cells.

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This strongly suggests that here may well be therapeutic benefits in addition to the CsA-sparing agent usage.

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Hou YC, Hsiu SL, Tsao CW et al: Acute intoxication of cyclosporin caused by coadministration of decoctions of the fruits of Citrus aurantium and the Pericarps of Citrus grandis.

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This slide shows the mean plasma concentration time course of indinavir in 8 healthy volunteers with indinavir alone or after taking indinavir with St.

Since the majority of these studies were conducted by one research group, studies need to be repeated in other laboratories to confirm these results.

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Compared to the classical strategy for diagnosis (fever refractive to antibacterial agents and the presence of pulmonary infiltrates on chest radiograph), the alternative strategy mentioned above would significantly reduce the number of patients receiving empirical therapy.

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Risk of first-generation H(1)-antihistamines: a GA(2)LEN position paper.

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It is distributed and expressed in the intestinal epithelium, hepatocytes, renal proximal tubular cells, and capillary endothelial cells.

Regrettably, many people (including a surprising number of physicians) are unaware of the very favorable risk-to-benefit ratio of such medications used in the doses that rheumatologists, ocular immunologists, and other specialists prescribe for immunomodulation of autoimmune disease.

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