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In this situation, the patient requires immediate re-evaluation with reassessment of the treatment regimen.

Through innovative public- private partnerships coupled with country-led programs, millions of the most vulnerable people will no longer have to worry about the devastating effects of this disease.

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In the face of these worsening conditions in the drug indus-try, was it a good idea for Merck to undertake an expensive project that showed littleeconomic promise?

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The World Health Organization recommends annual treatments with ivermectin to control the disease, the method currently employed by the two major multilateral efforts to control the disease: the African Programme for Onchocerciasis Control (APOC) and the Onchocerciasis Elimination Programme for the Americas (OEPA).

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April 1: The Carter Center Board of Trustees announces the appointment of Ambassador Mary Ann Peters as chief executive officer of The Carter Center, effective Sept.

To succeed in the years ahead, we must listen more and do more to make a positive difference in the lives of people around the world.

What, he pressed his colleagues, could Kimberly-Clark be passionate about?

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There are ongoing PELFs using albendazole and Mectizan in nine African countries and Yemen; these represent 35% of the total number of countries expected to require the co-administration of these two chemotherapeutic agents for LF elimination.

Similar differences in the responses of different species of mosquito to irrigation were observed with malaria vectors in Sri Lanka ().

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Onchocerciasis, or river blindness, was first reported in southwestern regions of Ethiopia in 1939, while the northwestern part of the country was recognized to be endemic in the 1970s.

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They may be large, solitary lesions, such as those seen following Toxoplasma infection, but sometimes they result in a "spotty" fundus appearance as seen in the presumed ocular histoplasmosis syndrome (POHS), birdshot chorioretinitis, multifocal choroiditis and pusctete inner choroidopathy (PIC).

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Sustainable management of both vectors and pathogens also demands additional measures to delay the selection of resistance genes that shorten the useful life of so many pesticides and drugs.

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In general, Merck does not sell or share personal information about you except as described in this policy and other applicable privacy notices, however, circumstances may arise where Merck may, for business reasons, decide to reorganize or divest its business through sale, merger or acquisition.

The role of climate change in an outbreak of malaria in Rwanda () was questioned because it coincided with a change in detection methods that was more likely to explain the jump in reported incidence of infections ().

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Projected changes in the average climate depend strongly on assumptions about the relationship between the global temperature and greenhouse gases produced by human activities ().

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Activities include assisting the nation with disease eradication and control programs, increasing food production, mediating conflict, observing elections, and promoting human rights.

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The cardiology franchise at Bayer already includes a number of marketed products and several other compounds in various stages of preclinical and clinical development.

The most useful ENSO-type information would be that which is relevant to forward planning in order to ensure adequate supplies of drugs or pesticides to meet any increase in vector populations ().

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More than 700 million people have been treated since the inception of the program with 80 million people still undergoing treatment in Africa, Latin America, and Yemen.

This treatment kills the larva but not the adult worms.

Annals of Tropical Medicine Parasitology 96 ( Suppl.

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The Carter Center Mental Health Program today released "The Carter Center Journalism Resource Guide on Behavioral Health" to journalists, behavioral health and media experts, and guests during the three-day annual meeting of the Rosalynn Carter Fellowships for Mental Health Journalism.

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We wanted everyoneto feel that, oh boy, building a brand-new airplane would be worthcontributing to!

Another subset of problematic infections is known as neglected tropical diseases (NTDs).

However, among persons who live in regions where the pathogen is endemic, reinfestation can occur rapidly, even when household contacts are also treated.

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We have been battling these invisible demons for 4 years!

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Local health workers, including these men, have dedicated countless hours to eradicating onchocerciasis in their communities.

There are widespread reports of irregularities and evidence of fraud, many of them ably recorded by Mary Anastasia O'Grady in The Wall Street Journal last week.

There are no data to guide coadministration of ISENTRESS with rifampin in patients below 18 years of age.

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When these expressions are used with regard to PELFs, they correspond to the number of average doses of Mectizan and standard doses of albendazole approved in a stated year and do correspond to the number of individuals to be treated since individuals are treated only one time per year in PELFs.

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The Colombia river blindness program did more than just rid the country of a horrible disease.

RESULTS: Despite treatment with Ivermectin, respiratory symptoms and chest radiological abnormalities persisted in all patients.

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Merck" name in North America, while its former parent company retains the rights in the rest of the world.

ZONTIVITY has not been studied as monotherapy.

Partners are also involved in vector control, surveillance, reporting, advocacy and other health and development activities, though mass distribution of ivermectin is at the core of the MDP.

Sometimes natural remedies are all that is available in certain remote areas.

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We are humbled by the great work of the alliance of partners to protect future generations from a disease that carries devastating implications for people, families, healthcare systems and local economies.

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Meles Zenawi requested President Carter's help to incorporate strong mechanisms for the protection of human rights into the structure of the Ethiopian state.

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The surge in funding has spawned numerous organizations dedicated to improving public health worldwide.

Hoerauf A, Mand S, Adjei O, Fleischer B, Buttner DW: Depletion of wolbachia endobacteria in Onchocerca volvulus by doxycycline and microfilaridermia after ivermectin treatment.

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The Carter Center's Onchocerciasis Elimination Program for the Americas (OPEA) is very close to eliminating transmission of the disease from its six endemic countries.

Waxman A ( 2001) Public-private health partnerships: a strategy for WHO.

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Their experience, and their difficulty finding affordable, effective, safe treatment, should serve as warnings that we ought to heed while we can.

Recently, Johnson and Johnson agreed not to enforce its patents on darunavir, a common retroviral, amid calls for other HIV medicines to be added to the Patent Pool.

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Resistance genes continue to be selected in malaria organisms (, ), causing resurgences in disease incidence.

Their combined work has strengthened systems, ensured universal health accessibility, and facilitated dialogue among member states, international institutions, and nonstate actors.

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This critical situation was compounded by the emigration of Ethiopia's skilled health professionals to other countries.

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Both systems are useful, but not exact, animal models.

Despite the differences in emphasis and focus on historical or future events, all authors agree that there are multifactorial causes of change in the incidence of vector-borne diseases.

These changes would make temperate environments more receptive to many tropical vector-borne diseases while having less negative effects on tropical environments.

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Instead, a descriptive study tries to de-to describe or explain the scribe or explain the world without reaching any conclusions about whether the worldworld without reaching is as it ought to be.

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Since 1988, ivermectin has been provided free of charge for use in humans by through the Mectizan donation program (MDP).

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Acceleration of the reduction in transmission can be achieved either by improving the implementation of annual CDTI, notably increasing CDTI treatment coverage, or by using alternative treatment strategies (ATS) where CDTI cannot be implemented effectively (in particular in areas co-endemic for loiasis), or CDTI effectiveness is considered sub-optimal.

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Confidence intervals for the reductions were calculated with the use of the variance of the binomial distribution.

They were also plastic enough to be understood in different ways by the various stakeholders, yet still have a common identity and provide some distance to the main stakeholders.

As defined by the Institute for Health Metrics and Evaluation (IHME), which replaces the previously used WHO chart of leading causes of disease, condition or injury.

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In a sense, we have seen the past, represented by the 200 millionth treatment and Mr.

Vector control or elimination continues to be conducted in selected areas using the safe and effective larvicide Abate (Temephos), donated by BASF.

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